Chiusi is part of Tuscany ("Toscana") and is placed halfway between Rome and Florence, both of which can easily be reached by car (through the Chiusi-Chianciano Junction on the A1 Rome-Florence highway 5 km from the house) and train (Chiusi Scalo station 2 km from the house, on the Rome-Florence line) in about one hour.

From Chiusi Scalo station it is also possible to reach Siena, Perugia and Arezzo with comfortable cross-country trains (30 minutes) or by car. Chiusi is in a very convenient part of South Tuscany, from where you can easily reach many small towns in Tuscany, Lazio and Umbria (the border between Tuscany and Umbria is just 4 Km. From Chiusi).

Other unmissable locations near Chiusi include : Chianciano Terme, famous for its baths, a recently opened Etruscan Museum and a lively programme of Summer shows, events and plays; Montepulciano, Medieval and Renaissance village in whose countryside the renowned wine "Nobile di Montepulciano" is produced: you can visit many open wine caves where it's possible to have free tastes of wine; Pienza, a true jewel of Renaissance architecture and art, planned by Pope Pius II Piccolomini and Leon Battista Alberti; Monticchiello, yet another wonderful Medieval village; Bagno Vignoni, a unique village with its main square consisting of an ancient bath; Montalcino, Medieval village, where is produced the famous wine "Brunello di Montalcino"; Cortona, an ancient Etruscan location but with important Medieval and Renaissance buildings; the Trasimeno Lake, with its islands, reachable by ferry; the medieval Citta' della Pieve, with frescos by Perugino; Monte Amiata with many nice typical little towns; from there you can drive to Monte Labro, where is the most important Buddhist community, in a very suggestive plateau called "European Tibet".